Document Details
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Document Type |
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Thesis |
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Document Title |
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Treatment Effect of Hordeum vulgara and Zizyphus jujube mixture on the kidney of male rats reared on drinking ground water from Hail city to Manifest Scientific Miracles in Sunnah( Histological and Ultrastructure Studies ) التأثير العلاجي لمخلوط الشعير و العناب على كلى ذكور الجرذان المرباة على شرب المياه الجوفية من مدينة حائل لإظهار الإعجاز العلمي في السنة ( دراسات نسيجية و تركيبية دقيقة ) |
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Subject |
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Sciences Faculty for Girls |
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Document Language |
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Arabic |
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Abstract |
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This research aims to study significant structural damages resulted by drinking contaminated ground water taken from HAIL area. Also, it aims to study the scientific miracles in characteristics of the Hordeume vulgare usage test for treating these structural damages upon mixing with Zizyphus jujube. The experiment was conducted on white male rats, which were divided into groups; First Group: Control Animals, consisting of 42 rats. The Second Group: consisting of 42 rats that were raised on drinking of the groundwater taken from Eastern BAGAA at HAIL Area for the duration of sixty (60) days. The Third Group: consisting of 42 rats that were raised the same as the second group, and a daily limited dose of the Hordeume vulgare and Zizyphus jujube mixture orally for sixty (60) days. autopsy was conducted on the test subjects after ten (10), thirty (30) and sixty (60) days of treatment. Biopsies of Kidney were also extracted and prepared for examination by the Electronic Microscope. The results were as follows: micro structural changes appeared in rats of the second group, and was represented in disorders in the structural organization of Glomerulis, for instance like; atrophy, inflation, and merge of glomeruli and fragmentation of capillaries, and dilation of urinary void. Changes also appeared in the proximal convoluted tubules level, and included hemophilia, expansion & bending of the basement membrane of proximal convoluted tubules as it fills with liquids. Where, the micro examination revealed that glomerulis are consisting of internal corrupted Epithelial Cells, that deposit red blood cells within the capillaries cavities, deformation of podocytes , cohesion of process, decomposition of some lining cells of nearby capillaries and differing of nucleus formation and rush of some into the cavity with brush border, and increase of the basement membrane's folds. In addition to deformation of the basement membrane in the distal convoluted tubules. The structural exam of the third group's rats' kidney biopsy revealed healthiness of cells and regaining of pattern structure. As it became similar to its peers in the controlled first group, as we notice decrease of the structural decomposition and regain of the regular structure of glomerulis and disappearance of hemorrhage areas in the interstitial tissue. Proximal convoluted tubules also regained its semi normal feature. Also, the effective influence of using the Hordeume vulgare and Zizyphus jujube mixture in reduction of severity of structural damages in distal tubules, as the hydrous decomposition in it. Also, in recovery of most lining cells of pyramids for its' pattern structure, as it contained ordinary depositions free cavities. Micro-examination results revealed the advantage of using wheat and grapes mixture in recovery of the kidney's normal structure, as the pyramids has shown its regular feature and basement membrane of the proximal tubules has been organized. Moreover, the internal lining epithelial cells of capillaries and mesangial cells has regained its normal feature, as the convoluted tubule has regained its regular structure, where wall cells appeared good and with constant edges in a depositions free cavity. The results confirmed the positive advantage of the Hordeume vulgare and Zizyphus jujube mixture and possibility of using it in order to avoid disadvantages of contaminated groundwater. |
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Supervisor |
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prof.Rahma Ali AL-Elyani |
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Thesis Type |
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Master Thesis |
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Publishing Year |
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1431 AH
2010 AD |
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Co-Supervisor |
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PROF.Sanaa Ahmed Khalifa |
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Added Date |
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Tuesday, June 15, 2010 |
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Researchers
| نشميه سندي الشمري | Al-shammary, Nashmeyah sandy | Researcher | Master | |
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